Tmem121b | transmembrane protein 121B

GeneMGI:2136977Synonyms: Cecr6

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Hematopoietic system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased neutrophil cell number2 supporting datasetsTmem121bem1(IMPC)TcphomozygoteEarly adult7.38x10-6 
abnormal skin morphology1 supporting datasetTmem121bem1(IMPC)TcphomozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetTmem121bem1(IMPC)TcphomozygoteEarly adult6.28x10-5 
decreased lymphocyte cell number1 supporting datasetTmem121bem1(IMPC)TcphomozygoteEarly adult4.29x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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