Morc3 | microrchidia 3

GeneMGI:2136841Synonyms: Zcwcc3, 1110051N18Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased exploration in new environment	1 supporting dataset	Morc3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.46x10^-6
increased neutrophil cell number	2 supporting datasets	Morc3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.63x10^-23
increased large unstained cell number	1 supporting dataset	Morc3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.65x10^-8
increased circulating aspartate transaminase level	1 supporting dataset	Morc3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.96x10^-11
decreased hematocrit	1 supporting dataset	Morc3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.39x10^-5
decreased lymphocyte cell number	1 supporting dataset	Morc3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.63x10^-14
preweaning lethality, complete penetrance	1 supporting dataset	Morc3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased erythrocyte cell number	1 supporting dataset	Morc3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	7.4x10^-5
increased monocyte cell number	2 supporting datasets	Morc3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.9x10^-14
increased circulating alanine transaminase level	1 supporting dataset	Morc3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.34x10^-17

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Morc3.

Associated images

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Histopathology

There is no histopathology data found for Morc3.

IMPC related publications

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External links

No external links available for Morc3.

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*Morc3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Morc3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Morc3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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