Pard3 | par-3 family cell polarity regulator
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Nervous system Vision/eye Hematopoietic system Mortality/aging
14 No significant impact
5 Not tested
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
| decreased basophil cell number | 1 supporting dataset | Pard3tm1b(KOMP)Wtsi | heterozygote | Early adult | 5.64x10-6 | ||
| abnormal optic disk morphology | 1 supporting dataset | Pard3tm1b(KOMP)Wtsi | heterozygote | Early adult | 8.03x10-6 | ||
| abnormal retina morphology | 1 supporting dataset | Pard3tm1b(KOMP)Wtsi | heterozygote | Early adult | 2.47x10-11 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pard3tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Pard3.
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| Pard3tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Pard3tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pard3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |