Ube2n | ubiquitin-conjugating enzyme E2N
Physiological systems
21 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Mortality/aging
13 No significant impact
3 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged thymus | 2 supporting datasets | Ube2nem1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Ube2nem1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| hyperactivity | 1 supporting dataset | Ube2nem1(IMPC)Ccpcz | heterozygote | Early adult | 3.18x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ube2nem1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Ube2nem1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal joint morphology | 1 supporting dataset | Ube2nem1(IMPC)Ccpcz | heterozygote | Early adult | 3.06x10-6 | ||
| abnormal thymus morphology | 2 supporting datasets | Ube2nem1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal seminal vesicle morphology | 1 supporting dataset | Ube2nem1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ube2nem1(IMPC)Ccpcz | homozygote | E9.5 | N/A * |
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External links
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| Ube2nem1(IMPC)Ccpcz | Exon Deletion | | mouse |
| Ube2ntm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Ube2ntm231418(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |