Rnf31 | ring finger protein 31

GeneMGI:1934704Synonyms: Paul, HOIP

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Embryo Growth/size/body region Nervous system Mortality/aging Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

29Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	1 supporting dataset	Rnf31^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Rnf31^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Rnf31^{tm1b(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Rnf31^{tm1b(KOMP)Wtsi}	homozygote	E15.5	N/A ^*
increased heart weight	2 supporting datasets	Rnf31^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	8.88x10^-6
abnormal hindbrain development	1 supporting dataset	Rnf31^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Rnf31^{tm1b(KOMP)Wtsi}	heterozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Rnf31^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
increased body length	1 supporting dataset	Rnf31^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	8.87x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf31.

Associated images

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Histopathology

There is no histopathology data found for Rnf31.

IMPC related publications

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External links

No external links available for Rnf31.

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*Rnf31^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rnf31^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rnf31^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Rnf31^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rnf31^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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