Alms1 | ALMS1, centrosome and basal body associated

GeneMGI:1934606Synonyms: Alstrom syndrome 1

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



increased circulating amylase level	1 supporting dataset	Alms1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.46x10^-9
abnormal locomotor behavior	1 supporting dataset	Alms1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.12x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Alms1.

Associated images

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Histopathology

There is no histopathology data found for Alms1.

IMPC related publications

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External links

No external links available for Alms1.

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*Alms1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Alms1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Alms1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	mouse

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