Alms1 | ALMS1, centrosome and basal body associated

GeneMGI:1934606Synonyms: Alstrom syndrome 1

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

17 No significant impact

5 Not tested

Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased circulating amylase level1 supporting datasetAlms1tm1b(EUCOMM)HmguhomozygoteEarly adult2.46x10-9 
abnormal locomotor behavior1 supporting datasetAlms1tm1b(EUCOMM)HmguhomozygoteEarly adult7.12x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Alms1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Alms1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Alms1tm1e(EUCOMM)HmguTargeted, non-conditional allelemouse

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