Jam3 | junction adhesion molecule 3
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Muscle Behavior/neurological Mortality/aging
13 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:49Adult tissues
53Embryo tissues
| abnormal sleep behavior | 1 supporting dataset | Jam3tm1.1(KOMP)Vlcg | heterozygote | Early adult | 4.49x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Jam3tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Jam3tm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.89x10-5 | ||
| abnormal skeletal muscle morphology | 1 supporting dataset | Jam3tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| male infertility | 1 supporting dataset | Jam3tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * |
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External links
No external links available for Jam3.
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| Jam3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Jam3tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Jam3tm92798(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |