Elovl4 | ELOVL fatty acid elongase 4

GeneMGI:1933331Synonyms: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Behavior/neurological Craniofacial Mortality/aging

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

6Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Elovl4^{tm2b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Elovl4^{tm2b(EUCOMM)Hmgu}	homozygote	E18.5	6.71x10^-6
decreased exploration in new environment	1 supporting dataset	Elovl4^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	2.31x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Elovl4.

Associated images

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Histopathology

There is no histopathology data found for Elovl4.

IMPC related publications

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External links

No external links available for Elovl4.

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*Elovl4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Elovl4^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Elovl4^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Elovl4^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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