Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1

GeneMGI:1933177Synonyms: 1810044J04Rik, BCAP

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased lymphocyte cell number1 supporting datasetPik3ap1tm1b(KOMP)WtsihomozygoteEarly adult2.55x10-7 
increased monocyte cell number2 supporting datasetsPik3ap1tm1b(KOMP)WtsihomozygoteEarly adult7.25x10-8 
increased neutrophil cell number2 supporting datasetsPik3ap1tm1b(KOMP)WtsihomozygoteEarly adult3.9x10-8 
abnormal cholesterol homeostasis1 supporting datasetPik3ap1tm1b(KOMP)WtsihomozygoteEarly adult2.05x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pik3ap1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Pik3ap1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Pik3ap1tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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