Lrba | LPS-responsive beige-like anchor

GeneMGI:1933162Synonyms: Lba, D3Ertd775e

Physiological systems

16 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Hearing/vestibular/ear Behavior/neurological Craniofacial

11 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal ear position	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	6.82x10^-6
increased circulating cholesterol level	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	4.29x10^-6
increased circulating amylase level	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	5.8x10^-12
increased circulating calcium level	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	2x10^-9
increased circulating creatinine level	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	2.65x10^-6
decreased circulating chloride level	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	7.75x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	6.18x10^-9
absent pinna reflex	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	2.84x10^-16
increased blood urea nitrogen level	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	1.26x10^-6
increased circulating total protein level	1 supporting dataset	Lrba^{em1(IMPC)Wtsi}	homozygote	Early adult	2.01x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lrba.

Associated images

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Histopathology

There is no histopathology data found for Lrba.

IMPC related publications

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External links

No external links available for Lrba.

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*Lrba^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*Lrba^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Lrba^{tm371894(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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