Acox3 | acyl-Coenzyme A oxidase 3, pristanoyl
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye
15 No significant impact
7 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased blood urea nitrogen level | 1 supporting dataset | Acox3em1(IMPC)J | homozygote | Early adult | 2.68x10-5 | ||
| cataract | 1 supporting dataset | Acox3em1(IMPC)J | homozygote | Early adult | 7.99x10-5 | ||
| impaired glucose tolerance | 1 supporting dataset | Acox3em1(IMPC)J | homozygote | Early adult | 4.84x10-6 |
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Human diseases caused by Acox3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Acox3.
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| Acox3em1(IMPC)Bay | Exon Deletion | | mouse |
| Acox3em1(IMPC)J | Exon Deletion | | mouse |
| Acox3tm42314(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Acox3tm42314(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |