Abtb1 | ankyrin repeat and BTB domain containing 1

GeneMGI:1933148Synonyms: EF1ABP, BPOZ

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Growth/size/body region Hematopoietic system Cardiovascular system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal skin morphology	1 supporting dataset	Abtb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.08x10^-5
abnormal heart morphology	1 supporting dataset	Abtb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased fasting circulating glucose level	1 supporting dataset	Abtb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.15x10^-5
enlarged heart	1 supporting dataset	Abtb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Abtb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Abtb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Abtb1.

Associated images

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Histopathology

There is no histopathology data found for Abtb1.

IMPC related publications

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External links

No external links available for Abtb1.

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*Abtb1^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Abtb1^{tm95114(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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