Plekha3 | pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3

GeneMGI:1932515Synonyms: FAPP1

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Behavior/neurological

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes



hyperactivity	6 supporting datasets	Plekha3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.68x10^-7
abnormal sleep behavior	1 supporting dataset	Plekha3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.36x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Plekha3.

Associated images

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Histopathology

There is no histopathology data found for Plekha3.

IMPC related publications

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External links

No external links available for Plekha3.

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*Plekha3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Plekha3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Plekha3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Plekha3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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