Rrbp1 | ribosome binding protein 1

GeneMGI:1932395Synonyms: p180, mRRp5.4, +12 more

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hearing/vestibular/ear Vision/eye Hematopoietic system Skeleton Mortality/aging

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral content	1 supporting dataset	Rrbp1^em1(IMPC)J	homozygote	Early adult	4.65x10^-5
abnormal auditory brainstem response	5 supporting datasets	Rrbp1^em1(IMPC)J	homozygote	Early adult	1.56x10^-10
decreased mean corpuscular hemoglobin	1 supporting dataset	Rrbp1^em1(IMPC)J	homozygote	Early adult	6.04x10^-8
decreased bone mineral density	1 supporting dataset	Rrbp1^em1(IMPC)J	homozygote	Early adult	3.67x10^-9
decreased mean corpuscular volume	1 supporting dataset	Rrbp1^em1(IMPC)J	homozygote	Early adult	2x10^-5
decreased circulating serum albumin level	1 supporting dataset	Rrbp1^em1(IMPC)J	homozygote	Early adult	1.15x10^-7
preweaning lethality, incomplete penetrance	1 supporting dataset	Rrbp1^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased lean body mass	1 supporting dataset	Rrbp1^em1(IMPC)J	homozygote	Early adult	1.58x10^-5
cataract	1 supporting dataset	Rrbp1^em1(IMPC)J	homozygote	Early adult	3.61x10^-6
decreased circulating total protein level	1 supporting dataset	Rrbp1^em1(IMPC)J	homozygote	Early adult	8.44x10^-15

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rrbp1.

Associated images

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Histopathology

There is no histopathology data found for Rrbp1.

IMPC related publications

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External links

No external links available for Rrbp1.

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*Rrbp1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Rrbp1^{tm50243(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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