Egfl8 | EGF-like domain 8

GeneMGI:1932094Synonyms: NG3

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Reproductive system Nervous system Behavior/neurological

18 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

hydrocephaly1 supporting datasetEgfl8tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
enlarged epididymis1 supporting datasetEgfl8tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal brain morphology1 supporting datasetEgfl8tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal epididymis morphology1 supporting datasetEgfl8tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
hyperactivity1 supporting datasetEgfl8tm1.1(KOMP)VlcghomozygoteEarly adult2.5x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Egfl8tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Egfl8tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Egfl8tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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