Dnajb12 | DnaJ heat shock protein family (Hsp40) member B12

GeneMGI:1931881Synonyms: mDj10

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Nervous system Behavior/neurological Mortality/aging

12 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues

Phenotypes

abnormal sleep behavior1 supporting datasetDnajb12tm1.1(KOMP)VlcgheterozygoteEarly adult1.45x10-5 
abnormal digit morphology1 supporting datasetDnajb12tm1.1(KOMP)VlcgheterozygoteEarly adult8.77x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetDnajb12tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased circulating sodium level1 supporting datasetDnajb12tm1.1(KOMP)VlcgheterozygoteEarly adult1.31x10-5 
abnormal spinal cord morphology1 supporting datasetDnajb12tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dnajb12tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Dnajb12tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Dnajb12tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dnajb12tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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