Chst5 | carbohydrate sulfotransferase 5
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging Cardiovascular system
16 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Chst5tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| cardiovascular system phenotype | 1 supporting dataset | Chst5tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 7.35x10-8 | ||
| increased heart rate variability | 1 supporting dataset | Chst5tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.2x10-8 | ||
| decreased exploration in new environment | 1 supporting dataset | Chst5tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.49x10-5 |
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Human diseases caused by Chst5 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Chst5.
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| Chst5tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Chst5tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Chst5tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Chst5tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |