Smpdl3a | sphingomyelin phosphodiesterase, acid-like 3A

GeneMGI:1931437Synonyms: 0610010C24Rik, ASML3A, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Integument Cardiovascular system

15 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology1 supporting datasetSmpdl3aem1(IMPC)TcphomozygoteEarly adultN/A * 
prolonged RR interval1 supporting datasetSmpdl3aem1(IMPC)TcphomozygoteEarly adult8.5x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Smpdl3aem1(IMPC)TcpExon Deletionmouse
Smpdl3atm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Smpdl3atm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Smpdl3atm42539(L1L2_Pgk_PM)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Smpdl3atm42539(L1L2_st2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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