Pate4 | prostate and testis expressed 4

GeneMGI:1930790Synonyms: Svs7, 9530004K16Rik, +2 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin concentration1 supporting datasetPate4tm1.1(KOMP)MbphomozygoteEarly adult5.99x10-5 
hyperactivity1 supporting datasetPate4tm1.1(KOMP)MbphomozygoteEarly adult2.55x10-7 
increased heart weight1 supporting datasetPate4tm1.1(KOMP)MbphomozygoteEarly adult7.91x10-5 
increased fasting circulating glucose level1 supporting datasetPate4tm1.1(KOMP)MbphomozygoteEarly adult8.71x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pate4tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Pate4tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Pate4tm1.1(KOMP)MbpReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Pate4tm458750(L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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