Myh10 | myosin, heavy polypeptide 10, non-muscle

GeneMGI:1930780Synonyms: myosin IIB, NMHC II-B, +10 more

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Embryo Growth/size/body region Cardiovascular system Mortality/aging

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



hemorrhage	1 supporting dataset	Myh10^em1(IMPC)J	homozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Myh10^em1(IMPC)J	homozygote	Early adult	N/A ^*
hemorrhage	1 supporting dataset	Myh10^em1(IMPC)J	homozygote	E12.5	N/A ^*
abnormal pericardium morphology	1 supporting dataset	Myh10^em1(IMPC)J	homozygote	E12.5	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Myh10^em1(IMPC)J	homozygote	E15.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Myh10^em1(IMPC)J	homozygote	E12.5	N/A ^*
abnormal skin coloration	1 supporting dataset	Myh10^em1(IMPC)J	homozygote	E15.5	N/A ^*
edema	1 supporting dataset	Myh10^em1(IMPC)J	homozygote	E15.5	N/A ^*
abnormal placenta size	1 supporting dataset	Myh10^em1(IMPC)J	homozygote	E15.5	N/A ^*
increased fasting circulating glucose level	1 supporting dataset	Myh10^em1(IMPC)J	heterozygote	Early adult	9.42x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Myh10.

Associated images

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Histopathology

There is no histopathology data found for Myh10.

IMPC related publications

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External links

No external links available for Myh10.

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*Myh10^em1(IMPC)J*	Indel	‌	mouse
*Myh10^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

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