Maged1 | MAGE family member D1

GeneMGI:1930187Synonyms: Dlxin-1, 5430405L04Rik, +4 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Cardiovascular system

18 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity8 supporting datasetsMaged1em1(IMPC)MbphomozygoteEarly adult1.07x10-32 
decreased vertical activity1 supporting datasetMaged1em1(IMPC)MbphomozygoteEarly adult8.56x10-5 
decreased heart rate1 supporting datasetMaged1em1(IMPC)MbphomozygoteEarly adult9.37x10-10 
increased freezing behavior1 supporting datasetMaged1em1(IMPC)MbphomozygoteEarly adult5.54x10-9 
prolonged RR interval1 supporting datasetMaged1em1(IMPC)MbphomozygoteEarly adult1.18x10-13 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Maged1em1(IMPC)MbpInter-exon deletionmouse
Maged1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Maged1tm86286(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Maged1tm86286(L1L2_gt0_Del_LacZ)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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