Zc3h8 | zinc finger CCCH type containing 8

GeneMGI:1930128Synonyms: Fliz1, E130108N08Rik

Physiological systems

21 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Limbs/digits/tail Liver/biliary system Hematopoietic system Skeleton Cardiovascular system Mortality/aging Renal/urinary system

11 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal skin morphology	2 supporting datasets	Zc3h8^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Zc3h8^{em1(IMPC)Ccpcz}	homozygote	E9.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Zc3h8^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
decreased CD8-positive, naive alpha-beta T cell number	1 supporting dataset	Zc3h8^{em1(IMPC)Ccpcz}	heterozygote	Early adult	2.19x10^-6
enlarged liver	1 supporting dataset	Zc3h8^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Zc3h8^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal digit morphology	1 supporting dataset	Zc3h8^{em1(IMPC)Ccpcz}	heterozygote	Early adult	2.67x10^-9
enlarged kidney	1 supporting dataset	Zc3h8^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Zc3h8^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Zc3h8^{em1(IMPC)Ccpcz}	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Zc3h8.

Associated images

Loading...

Histopathology

There is no histopathology data found for Zc3h8.

IMPC related publications

Loading...

External links

No external links available for Zc3h8.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Zc3h8^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Zc3h8^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Zc3h8^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Zc3h8^{tm35180(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes