Shank3 | SH3 and multiple ankyrin repeat domains 3

GeneMGI:1930016Synonyms: ProSAP2

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



decreased circulating calcium level	1 supporting dataset		Shank3^em1(IMPC)H	homozygote	Early adult		4.51x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Shank3.

Associated images

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Histopathology

There is no histopathology data found for Shank3.

IMPC related publications

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External links

No external links available for Shank3.

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*Shank3^em1(IMPC)H*	Exon Deletion	‌	mouse
*Shank3^em2(IMPC)H*	Exon Deletion	‌	mouse
*Shank3^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Shank3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Shank3^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	es cell
*Shank3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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