Trpm7 | transient receptor potential cation channel, subfamily M, member 7
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
14 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
| thrombocytosis | 1 supporting dataset | Trpm7tm1b(KOMP)Wtsi | heterozygote | Early adult | 2.69x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Trpm7tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Trpm7tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.88x10-12 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Trpm7tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * |
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External links
No external links available for Trpm7.
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| Trpm7tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Trpm7tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Trpm7tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Trpm7tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Trpm7tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Trpm7tm44236(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |