Smoc1 | SPARC related modular calcium binding 1

GeneMGI:1929878Synonyms: SPARC-related protein, 2600002F22Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

14 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Hematopoietic system Cardiovascular system Craniofacial Homeostasis/metabolism Pigmentation Limbs/digits/tail Nervous system Vision/eye Behavior/neurological Skeleton Mortality/aging

8 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:27Significant phenotypes

2Associated diseases

Expression examined in:92Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



short tibia	1 supporting dataset	Smoc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	0
abnormal digit morphology	5 supporting datasets	Smoc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.7x10^-10
abnormal retina morphology	1 supporting dataset	Smoc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.19x10^-6
narrow eye opening	1 supporting dataset	Smoc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	6.09x10^-11
abnormal head size	1 supporting dataset	Smoc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.87x10^-8
abnormal optic disk morphology	1 supporting dataset	Smoc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.28x10^-10
abnormal pelvic girdle bone morphology	1 supporting dataset	Smoc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.59x10^-6
mydriasis	1 supporting dataset	Smoc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.41x10^-6
abnormal retina blood vessel morphology	1 supporting dataset	Smoc1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.48x10^-7
increased basophil cell number	2 supporting datasets	Smoc1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.14x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Smoc1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Smoc1.

IMPC related publications

Loading...

External links

No external links available for Smoc1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Smoc1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Smoc1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Smoc1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes