Nampt | nicotinamide phosphoribosyltransferase
Physiological systems
22 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Nervous system Mortality/aging
20 No significant impact
2 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
47Embryo tissues
| abnormal brain morphology | 1 supporting dataset | Nampttm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Nampttm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Nampttm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| hydrocephaly | 1 supporting dataset | Nampttm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * |
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External links
No external links available for Nampt.
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| Nampttm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Nampttm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Nampttm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |