Rnf14 | ring finger protein 14

GeneMGI:1929668Synonyms: 2610005D23Rik, D7Bwg0165e, +3 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Skeleton Cardiovascular system Renal/urinary system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased heart weight	1 supporting dataset	Rnf14^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.39x10^-6
lordosis	1 supporting dataset	Rnf14^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.13x10^-6
abnormal kidney morphology	1 supporting dataset	Rnf14^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Rnf14^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased circulating HDL cholesterol level	1 supporting dataset	Rnf14^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.41x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf14.

Associated images

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Histopathology

There is no histopathology data found for Rnf14.

IMPC related publications

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External links

No external links available for Rnf14.

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*Rnf14^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Rnf14^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Rnf14^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Rnf14^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Rnf14^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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