Hacl1 | 2-hydroxyacyl-CoA lyase 1

GeneMGI:1929657Synonyms: 1600020H07Rik, Hpcl, +1 more

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Vision/eye Cardiovascular system

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged heart	1 supporting dataset	Hacl1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Hacl1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hacl1.

Associated images

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Histopathology

There is no histopathology data found for Hacl1.

IMPC related publications

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External links

No external links available for Hacl1.

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*Hacl1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Hacl1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hacl1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Hacl1^{tm43010(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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