Rsad2 | radical S-adenosyl methionine domain containing 2
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Cardiovascular system
16 No significant impact
5 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating phosphate level | 1 supporting dataset | Rsad2em1(IMPC)H | homozygote | Early adult | 1.1x10-5 | ||
| increased circulating creatinine level | 1 supporting dataset | Rsad2em1(IMPC)H | homozygote | Late adult | 3.23x10-10 | ||
| increased circulating potassium level | 1 supporting dataset | Rsad2em1(IMPC)H | homozygote | Late adult | 4.33x10-13 | ||
| decreased locomotor activity | 2 supporting datasets | Rsad2em1(IMPC)H | homozygote | Early adult | 2.4x10-6 | ||
| increased cardiac stroke volume | 1 supporting dataset | Rsad2em1(IMPC)H | homozygote | Late adult | 8.78x10-5 | ||
| abnormal behavior | 1 supporting dataset | Rsad2em1(IMPC)H | homozygote | Early adult | 2.56x10-5 | ||
| increased circulating serum albumin level | 1 supporting dataset | Rsad2em1(IMPC)H | homozygote | Late adult | 6.16x10-5 | ||
| decreased thigmotaxis | 2 supporting datasets | Rsad2em1(IMPC)H | homozygote | Early adult | 2.13x10-5 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Rsad2em1(IMPC)H | homozygote | Late adult | 4.72x10-5 |
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Human diseases caused by Rsad2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Rsad2.
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| Rsad2em1(IMPC)H | Exon Deletion | | mouse |
| Rsad2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Rsad2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |