Lamtor3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

GeneMGI:1929467Synonyms: Map2k1ip1, Mp1, +2 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Cardiovascular system Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased heart rate	1 supporting dataset	Lamtor3^{em1(IMPC)Hmgu}	heterozygote	Early adult	5.67x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Lamtor3^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*
prolonged RR interval	1 supporting dataset	Lamtor3^{em1(IMPC)Hmgu}	heterozygote	Early adult	1.02x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lamtor3.

Associated images

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Histopathology

There is no histopathology data found for Lamtor3.

IMPC related publications

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External links

No external links available for Lamtor3.

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*Lamtor3^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Lamtor3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Lamtor3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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