Lamtor3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Cardiovascular system Mortality/aging
18 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased heart rate | 1 supporting dataset | Lamtor3em1(IMPC)Hmgu | heterozygote | Early adult | 5.67x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Lamtor3em1(IMPC)Hmgu | homozygote | Early adult | N/A * | ||
| prolonged RR interval | 1 supporting dataset | Lamtor3em1(IMPC)Hmgu | heterozygote | Early adult | 1.02x10-7 |
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Human diseases caused by Lamtor3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Lamtor3.
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| Lamtor3em1(IMPC)Hmgu | Exon Deletion | | mouse |
| Lamtor3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Lamtor3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |