Bloc1s4 | biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino

GeneMGI:1929230Synonyms: Blos4, 2610101N07Rik, +1 more

Physiological systems

16 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Immune system Integument Vision/eye Hematopoietic system

10 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology2 supporting datasetsBloc1s4em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal skin morphology2 supporting datasetsBloc1s4em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal coat/hair pigmentation3 supporting datasetsBloc1s4em1(IMPC)MbphomozygoteEarly adult2.33x10-21 
decreased circulating total protein level1 supporting datasetBloc1s4em1(IMPC)MbphomozygoteEarly adult6.41x10-6 
increased monocyte cell number2 supporting datasetsBloc1s4em1(IMPC)MbphomozygoteEarly adult5.46x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bloc1s4em1(IMPC)MbpDeletionmouse
Bloc1s4tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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