Izumo1r | IZUMO1 receptor, JUNO

GeneMGI:1929185Synonyms: Folr4, 0910001L11Rik, +2 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Hematopoietic system Cardiovascular system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:152Adult tissues

25Embryo tissues

Phenotypes

Allele:

Phy. System:



female infertility	1 supporting dataset	Izumo1r^{tm2a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating fructosamine level	1 supporting dataset	Izumo1r^{tm2a(KOMP)Wtsi}	homozygote	Early adult	4.45x10^-5
increased circulating chloride level	1 supporting dataset	Izumo1r^{tm2a(KOMP)Wtsi}	homozygote	Early adult	4.99x10^-6
increased lean body mass	2 supporting datasets	Izumo1r^{tm2a(KOMP)Wtsi}	homozygote	Early adult	3.6x10^-6
decreased total body fat amount	1 supporting dataset	Izumo1r^{tm2a(KOMP)Wtsi}	homozygote	Early adult	3.75x10^-5
decreased circulating glucose level	1 supporting dataset	Izumo1r^{tm2a(KOMP)Wtsi}	homozygote	Early adult	1.24x10^-5
increased heart weight	1 supporting dataset	Izumo1r^{tm2a(KOMP)Wtsi}	homozygote	Early adult	2.12x10^-5
female infertility	1 supporting dataset	Izumo1r^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating amylase level	1 supporting dataset	Izumo1r^{tm2a(KOMP)Wtsi}	homozygote	Early adult	1.23x10^-5
increased red blood cell distribution width	1 supporting dataset	Izumo1r^{tm2a(KOMP)Wtsi}	homozygote	Early adult	3.25x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Izumo1r.

Associated images

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Histopathology

There is no histopathology data found for Izumo1r.

IMPC related publications

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External links

No external links available for Izumo1r.

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*Izumo1r^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Izumo1r^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Izumo1r^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Izumo1r^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Izumo1r^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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