Arpc1a | actin related protein 2/3 complex, subunit 1A
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Nervous system Skeleton Mortality/aging Craniofacial
13 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal pharyngeal arch morphology | 1 supporting dataset | Arpc1aem1(IMPC)J | homozygote | E9.5 | N/A * | ||
| decreased bone mineral content | 1 supporting dataset | Arpc1aem1(IMPC)J | heterozygote | Early adult | 6.3x10-6 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Arpc1aem1(IMPC)J | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Arpc1aem1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal neural tube closure | 1 supporting dataset | Arpc1aem1(IMPC)J | homozygote | E9.5 | N/A * |
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External links
No external links available for Arpc1a.
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| Arpc1aem1(IMPC)J | Exon Deletion | | mouse |
| Arpc1atm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Arpc1atm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |