Kcnd3 | potassium voltage-gated channel, Shal-related family, member 3
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Skeleton
15 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased thigmotaxis | 4 supporting datasets | Kcnd3em1(IMPC)J | homozygote | Early adult | 5.85x10-8 | ||
decreased exploration in new environment | 1 supporting dataset | Kcnd3em1(IMPC)J | homozygote | Early adult | 1.7x10-6 | ||
hyperactivity | 1 supporting dataset | Kcnd3em1(IMPC)J | homozygote | Early adult | 4.98x10-5 | ||
abnormal startle reflex | 1 supporting dataset | Kcnd3em1(IMPC)J | homozygote | Late adult | 2.92x10-5 | ||
hyperactivity | 7 supporting datasets | Kcnd3em1(IMPC)J | homozygote | Late adult | 1.69x10-8 | ||
increased vertical activity | 1 supporting dataset | Kcnd3em1(IMPC)J | homozygote | Early adult | 2.56x10-18 | ||
decreased locomotor activity | 1 supporting dataset | Kcnd3em1(IMPC)J | homozygote | Early adult | 1.12x10-6 | ||
increased bone mineral content | 1 supporting dataset | Kcnd3em1(IMPC)J | homozygote | Late adult | 3.97x10-6 | ||
decreased blood urea nitrogen level | 1 supporting dataset | Kcnd3em1(IMPC)J | homozygote | Early adult | 4.68x10-5 | ||
increased vertical activity | 1 supporting dataset | Kcnd3em1(IMPC)J | homozygote | Late adult | 5.97x10-8 |
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External links
No external links available for Kcnd3.
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Kcnd3em1(IMPC)J | Exon Deletion | | mouse |
Kcnd3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
Kcnd3tm44931(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |