Nisch | nischarin

GeneMGI:1928323Synonyms: 1200007D05Rik, edsn, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Skeleton Craniofacial

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



head bobbing	1 supporting dataset	Nisch^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.1x10^-7
increased circulating triglyceride level	1 supporting dataset	Nisch^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.1x10^-6
impaired glucose tolerance	1 supporting dataset	Nisch^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.67x10^-5
abnormal behavior	1 supporting dataset	Nisch^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.21x10^-5
head bobbing	1 supporting dataset	Nisch^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.58x10^-5
impaired glucose tolerance	1 supporting dataset	Nisch^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.73x10^-5
increased circulating cholesterol level	1 supporting dataset	Nisch^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.13x10^-6
decreased locomotor activity	2 supporting datasets	Nisch^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.59x10^-6
increased circulating phosphate level	1 supporting dataset	Nisch^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.47x10^-7
decreased thigmotaxis	1 supporting dataset	Nisch^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.21x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nisch.

Associated images

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Histopathology

There is no histopathology data found for Nisch.

IMPC related publications

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External links

No external links available for Nisch.

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*Nisch^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Nisch^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Nisch^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Nisch^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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