Trps1 | transcriptional repressor GATA binding 1

GeneMGI:1927616Synonyms: D15Ertd586e, trichorhinophalangeal syndrome I (human)

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetTrps1em1(IMPC)WtsihomozygoteEarly adultN/A * 
decreased fasting circulating glucose level1 supporting datasetTrps1em1(IMPC)WtsiheterozygoteEarly adult1.57x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Trps1em1(IMPC)WtsiDeletionmouse
Trps1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Trps1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Trps1tm95260(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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