Ykt6 | YKT6 v-SNARE homolog (S. cerevisiae)

GeneMGI:1927550Synonyms: 0610042I15Rik, 1810013M05Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased leukocyte cell number1 supporting datasetYkt6em1(IMPC)JheterozygoteEarly adult3.67x10-5 
preweaning lethality, complete penetrance1 supporting datasetYkt6em1(IMPC)JhomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetYkt6em1(IMPC)JhomozygoteE9.5N/A * 
increased exploration in new environment1 supporting datasetYkt6em1(IMPC)JheterozygoteEarly adult5.2x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ykt6em1(IMPC)JExon Deletionmouse
Ykt6tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ykt6tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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