Gmnn | geminin

GeneMGI:1927344Synonyms: Gem

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal lens morphology	1 supporting dataset	Gmnn^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	9.09x10^-8
cataract	1 supporting dataset	Gmnn^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	7.19x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Gmnn^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gmnn.

Associated images

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Histopathology

There is no histopathology data found for Gmnn.

IMPC related publications

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External links

No external links available for Gmnn.

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*Gmnn^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gmnn^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Gmnn^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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