Wdr12 | WD repeat domain 12

GeneMGI:1927241Synonyms: 4933402C23Rik, Ytm1p, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Pigmentation Integument Mortality/aging

16 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetWdr12tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal coat/hair pigmentation2 supporting datasetsWdr12tm1.1(KOMP)VlcgheterozygoteEarly adult2.11x10-6 
embryonic lethality prior to tooth bud stage1 supporting datasetWdr12tm1.1(KOMP)VlcghomozygoteE12.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetWdr12tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Wdr12tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Wdr12tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Wdr12tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Wdr12tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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