Nt5c3 | 5'-nucleotidase, cytosolic III

GeneMGI:1927186Synonyms: cN-III, 2610206B05Rik, +8 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Integument Vision/eye Hematopoietic system Skeleton

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetNt5c3em1(IMPC)TcphomozygoteEarly adult8.5x10-10 
enlarged lymph nodes1 supporting datasetNt5c3em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal skin morphology2 supporting datasetsNt5c3em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal lens morphology1 supporting datasetNt5c3em1(IMPC)TcphomozygoteEarly adult1x10-5 
abnormal eye morphology1 supporting datasetNt5c3em1(IMPC)TcphomozygoteEarly adultN/A * 
cataract1 supporting datasetNt5c3em1(IMPC)TcphomozygoteEarly adult1.53x10-5 
abnormal sternum morphology1 supporting datasetNt5c3em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nt5c3em1(IMPC)TcpExon Deletionmouse
Nt5c3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Nt5c3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Nt5c3tm43034(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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