Ppp1r15a | protein phosphatase 1, regulatory subunit 15A

GeneMGI:1927072Synonyms: Myd116, Gadd34

Physiological systems

14 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

12 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetPpp1r15aem2(IMPC)HhomozygoteEarly adult2.16x10-16 
decreased mean corpuscular hemoglobin1 supporting datasetPpp1r15aem2(IMPC)HhomozygoteEarly adult1.93x10-7 
increased circulating alanine transaminase level1 supporting datasetPpp1r15aem2(IMPC)HhomozygoteEarly adult3.19x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ppp1r15aem1(IMPC)HIndelmouse
Ppp1r15aem2(IMPC)HIndelmouse
Ppp1r15atm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Ppp1r15atm221653(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector

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