Zfp236 | zinc finger protein 236

GeneMGI:1926950Synonyms: LOC240456

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system Mortality/aging Cardiovascular system Renal/urinary system

13 No significant impact

2 Not tested

Gene metrics:16Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal spleen morphology2 supporting datasetsZfp236em1(IMPC)MbpheterozygoteLate adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetZfp236em1(IMPC)MbpheterozygoteLate adultN/A * 
enlarged epididymis1 supporting datasetZfp236em1(IMPC)MbpheterozygoteEarly adultN/A * 
enlarged spleen2 supporting datasetsZfp236em1(IMPC)MbpheterozygoteLate adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsZfp236em1(IMPC)MbphomozygoteEarly adultN/A * 
small heart1 supporting datasetZfp236em1(IMPC)MbpheterozygoteLate adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetZfp236em1(IMPC)MbphomozygoteE9.5N/A * 
abnormal urinary bladder morphology1 supporting datasetZfp236em1(IMPC)MbpheterozygoteLate adultN/A * 
abnormal heart shape1 supporting datasetZfp236em1(IMPC)MbpheterozygoteEarly adultN/A * 
enlarged kidney1 supporting datasetZfp236em1(IMPC)MbpheterozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp236em1(IMPC)MbpExon Deletionmouse

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