Pgap6 | post-glycosylphosphatidylinositol attachment to proteins 6

GeneMGI:1926283Synonyms: Rxylt1, Tmem8, +1 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Integument Behavior/neurological Mortality/aging

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	2 supporting datasets	Pgap6^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Pgap6^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Pgap6^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
male infertility	1 supporting dataset	Pgap6^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
no spontaneous movement	1 supporting dataset	Pgap6^em1(IMPC)Mbp	heterozygote	E18.5	N/A ^*
abnormal testis morphology	1 supporting dataset	Pgap6^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pgap6.

Associated images

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Histopathology

There is no histopathology data found for Pgap6.

IMPC related publications

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External links

No external links available for Pgap6.

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*Pgap6^em1(IMPC)Mbp*	Insertion, Intragenic deletion	‌	mouse
*Pgap6^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pgap6^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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