Wrnip1 | Werner helicase interacting protein 1

GeneMGI:1926153Synonyms: WHIP, 4833444L21Rik

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Digestive/alimentary Vision/eye Behavior/neurological

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total retina thickness	2 supporting datasets	Wrnip1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.24x10^-8
enlarged cecum	2 supporting datasets	Wrnip1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased locomotor activity	3 supporting datasets	Wrnip1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.25x10^-5
abnormal retina morphology	1 supporting dataset	Wrnip1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.43x10^-8
abnormal seminal vesicle morphology	1 supporting dataset	Wrnip1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Wrnip1.

Associated images

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Histopathology

There is no histopathology data found for Wrnip1.

IMPC related publications

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External links

No external links available for Wrnip1.

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*Wrnip1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Wrnip1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Wrnip1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Wrnip1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Wrnip1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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