Arid1b | AT-rich interaction domain 1B

GeneMGI:1926129Synonyms: 9330189K18Rik, B230217J03Rik

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Nervous system Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



decreased locomotor activity	4 supporting datasets	Arid1b^em1(IMPC)Tcp	heterozygote	Early adult	2.18x10^-7
increased freezing behavior	2 supporting datasets	Arid1b^em1(IMPC)Tcp	heterozygote	Early adult	4.01x10^-6
increased circulating creatinine level	1 supporting dataset	Arid1b^em1(IMPC)Tcp	heterozygote	Early adult	8.84x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Arid1b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal freezing behavior	1 supporting dataset	Arid1b^em1(IMPC)Tcp	heterozygote	Early adult	1.02x10^-5
male infertility	1 supporting dataset	Arid1b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Arid1b^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased fasting circulating glucose level	1 supporting dataset	Arid1b^em1(IMPC)Tcp	heterozygote	Early adult	1.16x10^-5
edema	1 supporting dataset	Arid1b^em1(IMPC)Tcp	homozygote	E15.5	N/A ^*
decreased prepulse inhibition	3 supporting datasets	Arid1b^em1(IMPC)Tcp	heterozygote	Early adult	2.23x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arid1b.

Associated images

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Histopathology

There is no histopathology data found for Arid1b.

IMPC related publications

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External links

No external links available for Arid1b.

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*Arid1b^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Arid1b^{tm1(IMPC)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Arid1b^{tm1.2(IMPC)Wtsi}*	Reporter-tagged deletion allele (post Flp, with no reporter and selection cassette)	‌	mouse
*Arid1b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Arid1b^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Arid1b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Arid1b^{tm42688(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Arid1b^{tm42688(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Arid1b^{tm47092(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes