Pdk1 | pyruvate dehydrogenase kinase, isoenzyme 1

GeneMGI:1926119Synonyms: D530020C15Rik

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small testis	1 supporting dataset	Pdk1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Pdk1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pdk1.

Associated images

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Histopathology

There is no histopathology data found for Pdk1.

IMPC related publications

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External links

No external links available for Pdk1.

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*Pdk1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Pdk1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Pdk1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pdk1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Pdk1^{tm27384(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes