Ubash3a | ubiquitin associated and SH3 domain containing, A

GeneMGI:1926074Synonyms: 5830413C03Rik, Sts-2, +1 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological Cardiovascular system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



decreased circulating triglyceride level	1 supporting dataset	Ubash3a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.53x10^-5
cataract	1 supporting dataset	Ubash3a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.58x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Ubash3a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.7x10^-6
abnormal lens morphology	1 supporting dataset	Ubash3a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.21x10^-6
decreased grip strength	2 supporting datasets	Ubash3a^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.79x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ubash3a.

Associated images

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Histopathology

There is no histopathology data found for Ubash3a.

IMPC related publications

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External links

No external links available for Ubash3a.

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*Ubash3a^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ubash3a^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ubash3a^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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