Fbxo43 | F-box protein 43

GeneMGI:1926053Synonyms: XErp1 homolog, endogenous meiotic inhibitor 2, +3 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Immune system Growth/size/body region Hematopoietic system Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased mean platelet volume	1 supporting dataset	Fbxo43^{em1(IMPC)Marc}	homozygote	Early adult	1.13x10^-6
increased eosinophil cell number	2 supporting datasets	Fbxo43^{em1(IMPC)Marc}	homozygote	Early adult	1.54x10^-40
female infertility	1 supporting dataset	Fbxo43^{em1(IMPC)Marc}	homozygote	Early adult	N/A ^*
increased hematocrit	1 supporting dataset	Fbxo43^{em1(IMPC)Marc}	homozygote	Early adult	9.24x10^-6
increased erythrocyte cell number	1 supporting dataset	Fbxo43^{em1(IMPC)Marc}	homozygote	Early adult	8.3x10^-7
increased basophil cell number	2 supporting datasets	Fbxo43^{em1(IMPC)Marc}	homozygote	Early adult	1.45x10^-38
male infertility	1 supporting dataset	Fbxo43^{em1(IMPC)Marc}	homozygote	Early adult	N/A ^*
increased heart weight	1 supporting dataset	Fbxo43^{em1(IMPC)Marc}	homozygote	Early adult	5.05x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fbxo43.

Associated images

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Histopathology

There is no histopathology data found for Fbxo43.

IMPC related publications

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External links

No external links available for Fbxo43.

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*Fbxo43^{em1(IMPC)Marc}*	Deletion	‌	mouse
*Fbxo43^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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