Pabir2 | PABIR family member 2

GeneMGI:1926005Synonyms: Fam122b, 4632404H22Rik

Physiological systems

23 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Craniofacial

11 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal testis morphology	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*
small testis	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small stomach	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	hemizygote	Early adult	N/A ^*
hyperactivity	1 supporting dataset	Pabir2^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.88x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pabir2.

Associated images

16 images

X-ray

XRay Images Forepaw

32 images

X-ray

XRay Images Hind Leg and Hip

16 images

X-ray

XRay Images Skull Dorso Ventral Orientation

16 images

X-ray

XRay Images Skull Lateral Orientation

32 images

X-ray

XRay Images Whole Body Dorso Ventral

16 images

X-ray

XRay Images Whole Body Lateral Orientation

Human diseases caused by Pabir2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.



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Histopathology

There is no histopathology data found for Pabir2.

IMPC related publications

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External links

No external links available for Pabir2.

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*Pabir2^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Pabir2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes

Pabir2 | PABIR family member 2

Physiological systems

12 Significantly impacted by the knock-out

11 No significant impact

1 Not tested

Data collections

Phenotypes

lacZ Expression

Associated images

X-ray

X-ray

X-ray

X-ray

X-ray

X-ray

Human diseases caused by Pabir2 mutations

Histopathology

IMPC related publications

External links

Order Mouse and ES Cells

The IMPC Newsletter

Access Data Release 22.1 Data