Ccdc88b | coiled-coil domain containing 88B
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Renal/urinary system
13 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased lymphocyte cell number | 1 supporting dataset | Ccdc88bem1(IMPC)Tcp | homozygote | Early adult | 9.76x10-7 | ||
| decreased leukocyte cell number | 1 supporting dataset | Ccdc88bem1(IMPC)Tcp | homozygote | Early adult | 2.4x10-7 | ||
| polycystic kidney | 1 supporting dataset | Ccdc88bem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Ccdc88bem1(IMPC)Tcp | homozygote | Early adult | 6.39x10-5 | ||
| enlarged lymph nodes | 1 supporting dataset | Ccdc88bem1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Ccdc88b mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ccdc88b.
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| Ccdc88bem1(IMPC)Tcp | Inter-exon deletion | | mouse |
| Ccdc88btm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |